Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25919211 | 0.91 | OPRM1 (0.41) | OPRM1OPRK1OPRL1 | |
| SCHEMBL24663477 | 0.85 | OPRM1 (0.55) | OPRM1OPRK1OPRL1MAOA | |
| SCHEMBL7983234 | 0.79 | OPRM1 (0.42) | OPRM1OPRK1OPRL1PNMTMAOA | |
| SCHEMBL25919691 | 0.79 | OPRM1 (0.36) | OPRM1OPRK1OPRL1 | |
| SCHEMBL25935275 | 0.78 | CCR2 (0.41) | MAOAMAOB | |
| SCHEMBL23794418 | 0.74 | SLC6A3 (0.45) | — | |
| SCHEMBL775522 | 0.70 | SLC6A2 (0.47) | OPRM1 | |
| SCHEMBL776948 | 0.70 | DPP4 (0.45) | OPRM1 | |
| SCHEMBL24638233 | 0.69 | ESR2 (0.54) | OPRM1 | |
| SCHEMBL25919201 | 0.69 | LIG1 (0.33) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |