Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033804 | 0.94 | KMT2A (0.53) | ALDH1A1KMT2AUSP2SMN1; SMN2MAPT | |
| SCHEMBL1719092 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTLMNAGAA | |
| SCHEMBL29827991 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTLMNAGAA | |
| SCHEMBL1499037 | 0.78 | GLA (0.49) | ALDH1A1KMT2AUSP2SMN1; SMN2MAPT | |
| SCHEMBL9928605 | 0.77 | MAPT (0.47) | ALDH1A1KMT2AUSP2SMN1; SMN2MAPT | |
| SCHEMBL14861898 | 0.77 | CFTR (0.55) | ALDH1A1KMT2AUSP2SMN1; SMN2MAPT | |
| SCHEMBL15922616 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AUSP2SMN1; SMN2MAPT | |
| SCHEMBL30134211 | 0.77 | MAPT (0.47) | ALDH1A1KMT2AUSP2SMN1; SMN2MAPT | |
| SCHEMBL18412886 | 0.73 | PKM (0.52) | ALDH1A1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL22208505 | 0.73 | MAPK1 (0.47) | ALDH1A1KMT2AUSP2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138293-A1 | 2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-11-10 | — | — | WO | disclosed |