Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25315075 | 0.87 | HRH3 (0.39) | HRH3HTR1AHTR1DHTR1BGPR119 | |
| SCHEMBL6074522 | 0.80 | NOTUM (0.49) | DRD3KDM4E | |
| SCHEMBL25314670 | 0.71 | DRD2 (0.45) | HTR1ADRD3 | |
| SCHEMBL25315811 | 0.70 | HTR1A (0.41) | HTR1ADRD3KDM4EALDH1A1LMNA | |
| SCHEMBL10860142 | 0.68 | MAPT (0.44) | KDM4EALDH1A1LMNA | |
| SCHEMBL18756604 | 0.67 | PER2 (0.46) | HTR1AHTR1DHTR1BDRD3ALOX15 | |
| SCHEMBL10856750 | 0.62 | MAPT (0.42) | KDM4EALDH1A1 | |
| SCHEMBL31714475 | 0.62 | HTR1A (0.41) | HTR1AHTR1DHTR1BKDM4EALDH1A1 | |
| SCHEMBL11071120 | 0.62 | TRIM24 (0.49) | — | |
| SCHEMBL1239759 | 0.61 | TRIM24 (0.48) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |