Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 1/20 | 0.46 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.46 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD5 | P21918 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477918 | 0.89 | NOTUM (0.44) | PER2CRY1CRY2MEN1KMT2A | |
| SCHEMBL20857619 | 0.80 | PER2 (0.52) | PER2CRY1CRY2MEN1KMT2A | |
| SCHEMBL3319807 | 0.80 | DRD4 (0.42) | PER2CRY1CRY2MEN1KMT2A | |
| SCHEMBL25431591 | 0.77 | MEN1 (0.40) | PER2CRY1CRY2MEN1KMT2A | |
| SCHEMBL19080479 | 0.77 | PER2 (0.43) | PER2CRY1CRY2MEN1KMT2A | |
| SCHEMBL25314670 | 0.75 | DRD2 (0.45) | DRD2DRD5DRD3DRD1DRD4 | |
| SCHEMBL4963960 | 0.75 | SLC6A2 (0.49) | PER2CRY1CRY2MEN1KMT2A | |
| SCHEMBL31714475 | 0.75 | HTR1A (0.41) | KMT2AALDH1A1HSD17B3DRD2DRD1 | |
| SCHEMBL4963829 | 0.74 | SLC6A2 (0.43) | PER2CRY1CRY2MEN1KMT2A | |
| SCHEMBL18195193 | 0.73 | MAOA (0.53) | KMT2ANOTUMHSD17B3DRD2DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476606-A | Benzosultams and analogs and their use as fungicides | 拜耳作物科学股份公司 | 2019-03-15 | — | — | CN | disclosed |
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | ERG28, RPL23, RPL10 | PER2 3720/4885CRY1 4113/4885CRY2 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.