Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31698360 | 0.87 | ABL1 (0.39) | HCAR1ABL1 | |
| SCHEMBL31698374 | 0.77 | HCAR1 (0.38) | HCAR1 | |
| SCHEMBL25922298 | 0.77 | PRPS1 (0.41) | HCAR1 | |
| SCHEMBL31698308 | 0.74 | HCAR1 (0.34) | HCAR1ABL1 | |
| SCHEMBL31698452 | 0.72 | AR (0.41) | HCAR1ABL1 | |
| SCHEMBL31349605 | 0.72 | HCAR1 (0.33) | HCAR1 | |
| SCHEMBL31698506 | 0.71 | MEN1 (0.45) | HCAR1 | |
| SCHEMBL31698068 | 0.69 | ABL1 (0.37) | ABL1 | |
| SCHEMBL11779175 | 0.67 | PTGS2 (0.38) | — | |
| SCHEMBL31349425 | 0.67 | HCAR1 (0.33) | HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |