Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434929 | 0.78 | IDO1 (0.42) | AR | |
| SCHEMBL3022860 | 0.73 | KIF11 (0.52) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL30368360 | 0.73 | KIF11 (0.52) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL257926 | 0.72 | ESR1 (0.41) | MIFARESR2ADRA2AADRA2B | |
| SCHEMBL10034978 | 0.72 | NR1I2 (0.45) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL29427019 | 0.72 | NR1I2 (0.45) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL30595362 | 0.72 | ALDH1A1 (0.60) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL5792355 | 0.72 | GLA (0.54) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL31256038 | 0.72 | GLA (0.54) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL5511642 | 0.72 | ALDH1A1 (0.60) | NR1I2ALDH1A1LMNACYP2C9MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |