Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566097 | 0.76 | ALDH1A1 (0.42) | — | |
| SCHEMBL13077269 | 0.73 | ALOX15 (0.44) | ESR1ESR2MIF | |
| SCHEMBL21737149 | 0.73 | CCR2 (0.34) | — | |
| SCHEMBL257618 | 0.73 | DGAT1 (0.39) | — | |
| SCHEMBL25922969 | 0.72 | NR1I2 (0.41) | ESR2ADRA2AADRA2BADRA2CMIF | |
| Ethane SCHEMBL27895933 | 0.70 | ESR1 (0.46) | ESR1ESR2ADRA2AADRA2BADRA2C | |
| SCHEMBL29617579 | 0.69 | — | — | |
| SCHEMBL15677 | 0.69 | — | — | |
| SCHEMBL257925 | 0.69 | — | — | |
| Ethane SCHEMBL27680183 | 0.69 | ESR1 (0.57) | ESR1ESR2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| EP-2073816-B1 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS INC (US) | 2011-09-14 | — | — | EP | disclosed |