SCHEMBL5511642

SCHEMBL5511642

Oc1ccc(O)c(C(F)(F)F)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
NR1I2 O75469 1/20 0.60
LMNA P02545 1/20 0.60
CYP2C9 P11712 1/20 0.60
MIF P14174 1/20 0.60
TYR P14679 1/20 0.60
ALOX15 P16050 1/20 0.60
HTT P42858 1/20 0.60
NFE2L2 Q16236 1/20 0.60
HSD17B10 Q99714 1/20 0.60
HSD17B1 P14061 4/20 0.53
HSD17B2 P37059 4/20 0.53
KIF11 P52732 2/20 0.45
HSD17B3 P37058 1/20 0.43
APP P05067 1/20 0.41
AR P10275 3/20 0.40
ESR2 Q92731 2/20 0.40
ESR1 P03372 1/20 0.40
GAA P10253 1/20 0.40
P2RX1 P51575 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30595362 1.00 ALDH1A1 (0.60) ALDH1A1NR1I2LMNACYP2C9MIF
Phenol SCHEMBL27565730 0.89 HSD17B1 (0.54) ALDH1A1NR1I2LMNACYP2C9MIF
SCHEMBL30368360 0.82 KIF11 (0.52) ALDH1A1NR1I2LMNACYP2C9MIF
SCHEMBL3022860 0.82 KIF11 (0.52) ALDH1A1NR1I2LMNACYP2C9MIF
SCHEMBL29319816 0.81 ALDH1A1 (0.56) ALDH1A1NR1I2LMNACYP2C9MIF
SCHEMBL9575224 0.81 ALDH1A1 (0.56) ALDH1A1NR1I2LMNACYP2C9MIF
SCHEMBL26982546 0.81 ALDH1A1 (0.68) ALDH1A1NR1I2LMNACYP2C9MIF
SCHEMBL31256038 0.80 GLA (0.54) ALDH1A1NR1I2LMNACYP2C9MIF
SCHEMBL29485676 0.80 HSD17B1 (0.65) HSD17B1HSD17B2KIF11APPAR
SCHEMBL1938893 0.80 HSD17B1 (0.65) HSD17B1HSD17B2KIF11APPAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117916215-A Indene compound, pharmaceutical composition thereof and therapeutic application thereof 藤济(厦门)生物医药科技有限公司 2024-04-19 CN claimed
CN-106750301-B Sulfonated polyether sulfone copolymer containing pyridine groups, preparation method and application 中国工程物理研究院化工材料研究所 2019-03-22 CN claimed
CN-106750191-B Sulfonated polyether ketone copolymers of the main chain containing pyridine groups, preparation method and application 中国工程物理研究院化工材料研究所 2018-10-26 CN claimed
CN-105601906-B Sulfonated poly aryl ether ketone cross linking membrane of sulfur-bearing ehter bond and preparation method thereof 中国工程物理研究院化工材料研究所 2018-02-16 CN claimed
CN-106750301-A Sulfonated polyether sulfone copolymer containing pyridine groups, preparation method and application 中国工程物理研究院化工材料研究所 2017-05-31 CN claimed
CN-106750191-A Sulfonated polyether ketone copolymers, preparation method and application of the main chain containing pyridine groups 中国工程物理研究院化工材料研究所 2017-05-31 CN claimed
CN-104860808-B Two fluorine monomers containing tetraphenyl ethylene group and be used for preparing poly aryl ether ketone polymer 吉林大学 2016-09-07 CN claimed
CN-105601906-A Sulfonated poly aryl ether ketone cross-linking membrane containing thioether keys and preparing method thereof INST CHEMICAL MAT CHINA ACAD ENG PHYSICS 2016-05-25 CN claimed
CN-101265193-A Method for preparing 2,5-di(2,6-dinitro-4-trifluoromethylphenoxy)trifluorotoluene UNIV DONGHUA (CN) 2008-09-17 CN claimed
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed
CN-117916215-A Indene compound, pharmaceutical composition thereof and therapeutic application thereof 藤济(厦门)生物医药科技有限公司 2024-04-19 CN disclosed
US-20240083860-A1 AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FUKANG SHANGHAI HEALTH TECH CO LTD (CN) 2024-03-14 US disclosed
EP-4303217-A1 AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Fukang (Shanghai) Health Technology Co., Ltd. (CN) 2024-01-10 EP disclosed
WO-1996028491-A1 SOLUBLE FLUORINATED POLY-P-PHENYLENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-19 WO disclosed
WO-1992021688-A1 NEW PERFLUOROALKYLATED AMPHIPHILIC PHOSPHORUS COMPOUNDS: PREPARATION AND BIOMEDICAL APPLICATIONS S.A. A.T.T.A. APPLICATIONS ET TRANSFERTS DE TECHN OLOGIES AVANCEES (FR) 1992-12-10 WO disclosed
EP-0032063-B1 NOVEL SUBSTITUTED ARYLENE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1984-03-14 EP disclosed
US-4351950-A Anti-arteriosclerotic agents WARNER-LAMBERT COMPANY (US) 1982-09-28 US disclosed
EP-0032063-A2 Novel substituted arylene compounds and processes for their production WARNER-LAMBERT COMPANY (US) 1981-07-15 EP disclosed
US-4248618-A Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof ICI AUSTRALIA LIMITED (AU) 1981-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240083860-A1 AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SLC10A1, GOT1, CYP46A1 ALDH1A1 354/4885NR1I2 879/4885LMNA 2220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.