SCHEMBL25923622

SCHEMBL25923622

CC(C)=NOCc1cccc(F)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.53
AGXT P21549 2/20 0.53
MAOB P27338 10/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CYP3A4 P08684 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
TSHR P16473 1/20 0.49
MAOA P21397 1/20 0.47
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
STAT1 P42224 1/20 0.45
RAB9A P51151 1/20 0.45
HCAR2 Q8TDS4 1/20 0.44
NR4A2 P43354 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28324018 0.83 IDO1 (0.50) IDO1AGXTMAOBSMN1; SMN2MAOA
SCHEMBL25923623 0.81 CYP3A4 (0.55) IDO1AGXTMAOBCYP3A4CYP2C9
SCHEMBL2755831 0.81 IDO1 (0.55) IDO1MAOBCYP3A4CYP2C9CYP2C19
SCHEMBL16202052 0.78 SMN1; SMN2 (0.47) IDO1AGXTMAOBSMN1; SMN2MAOA
SCHEMBL17986310 0.78 IDO1 (0.60) IDO1AGXTMAOBSMN1; SMN2MAOA
SCHEMBL3265545 0.78 IDO1 (0.57) IDO1AGXTMAOBSMN1; SMN2CYP3A4
SCHEMBL678711 0.77 MAPT (0.57) IDO1MAOBSMN1; SMN2CYP3A4CYP2C9
SCHEMBL10102301 0.77 RAB9A (0.47) IDO1AGXTMAOBSMN1; SMN2RAB9A
SCHEMBL25923630 0.77 MAOB (0.49) MAOBSMN1; SMN2CYP3A4CYP2C9CYP2C19
SCHEMBL21518127 0.77 IDO1 (0.58) IDO1AGXTMAOBCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-26 US disclosed
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-26 US disclosed
US-20230232827-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-27 US disclosed
US-20230232827-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE CYC1, SQOR, MT-CO1 IDO1 1021/4885AGXT 712/4885MAOB 227/4885
US-20230232827-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES CYC1, SQOR, MT-CO3 IDO1 1034/4885AGXT 378/4885MAOB 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.