SCHEMBL25924057

SCHEMBL25924057

O=CCN1CC2(CC(NC3CC3)C2)C1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.31
ADH1A P07327 1/20 0.31
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21088586 0.83 KDM1A (0.31) KDM1A
SCHEMBL25923845 0.76 ALOX15 (0.33) KDM1A
SCHEMBL20106792 0.76 KDM1A (0.44) KDM1A
SCHEMBL25923913 0.76 KDM1A (0.33) KDM1A
SCHEMBL15777304 0.75 ADH1B (0.37) ADH1BADH1A
SCHEMBL21088777 0.75 KDM1A (0.40) KDM1A
SCHEMBL25923992 0.73 L3MBTL1 (0.40) KDM1A
SCHEMBL21088369 0.72 POLB (0.38) KDM1A
SCHEMBL21088400 0.72 KDM1A (0.32) KDM1A
SCHEMBL20106817 0.72 KDM1A (0.30) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3532459-B1 LSD1 INHIBITORS AND MEDICAL USES THEREOF CONSTELLATION PHARMACEUTICALS INC (US) 2023-08-02 EP disclosed