SCHEMBL20106792

SCHEMBL20106792

OCCN1CC2(CC(NC3CC3)C2)C1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.44
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25923906 0.82 KDM1A (0.46) KDM1APKMKMT2A
SCHEMBL25923845 0.81 ALOX15 (0.33) KDM1A
SCHEMBL21088777 0.80 KDM1A (0.40) KDM1A
SCHEMBL25923992 0.78 L3MBTL1 (0.40) KDM1A
SCHEMBL20106817 0.77 KDM1A (0.30) KDM1A
SCHEMBL21088400 0.77 KDM1A (0.32) KDM1A
SCHEMBL25923913 0.77 KDM1A (0.33) KDM1A
SCHEMBL25924057 0.76 ADH1B (0.31) KDM1A
SCHEMBL25923869 0.76 NPSR1 (0.33) KDM1A
SCHEMBL20107004 0.75 KDM1A (0.30) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3532459-B1 LSD1 INHIBITORS AND MEDICAL USES THEREOF CONSTELLATION PHARMACEUTICALS INC (US) 2023-08-02 EP disclosed
WO-2018081343-A1 LSD1 INHIBITORS AND MEDICAL USES THEREOF CONSTELLATION PHARMACEUTICALS, INC. (US) 2018-05-03 WO disclosed