Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480581 | 0.85 | NCF1 (0.34) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL24480575 | 0.85 | NCF1 (0.36) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL24480589 | 0.83 | NCF1 (0.33) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL14996488 | 0.81 | NCF1 (0.43) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL24480578 | 0.81 | NCF1 (0.35) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL29317306 | 0.79 | CACNA2D1 (0.34) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL24480840 | 0.79 | L3MBTL3 (0.33) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL18898618 | 0.78 | NCF1 (0.41) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25924745 | 0.78 | KMT2A (0.32) | — | |
| SCHEMBL24204800 | 0.78 | NCF1 (0.43) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |