Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3514895 | 0.87 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2TP53LMNAL3MBTL1 | |
| SCHEMBL2067150 | 0.83 | CCNC (0.43) | ALDH1A1SMN1; SMN2TP53LMNAL3MBTL1 | |
| SCHEMBL1559248 | 0.82 | MITF (0.51) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL25925092 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TP53LMNAL3MBTL1 | |
| SCHEMBL2066748 | 0.80 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TP53LMNAPOLB | |
| SCHEMBL18463627 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TP53LMNAL3MBTL1 | |
| SCHEMBL1559636 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TP53LMNAL3MBTL1POLB | |
| SCHEMBL20555214 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TP53LMNAL3MBTL1POLB | |
| SCHEMBL20555415 | 0.76 | MAPK1 (0.46) | ALDH1A1SMN1; SMN2TP53LMNAL3MBTL1 | |
| SCHEMBL20555414 | 0.76 | MAPK1 (0.46) | ALDH1A1SMN1; SMN2TP53LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | C9, C5, C1QBP | ALDH1A1 1023/4885SMN1; SMN2 2279/4885TP53 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.