Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925358 | 0.82 | MAPT (0.54) | STAT3SMN1; SMN2GAAPTGDR2MAPT | |
| SCHEMBL19208909 | 0.81 | STAT3 (0.59) | STAT3SMN1; SMN2GAAMAPTPOLB | |
| SCHEMBL29781691 | 0.81 | STAT3 (0.59) | STAT3SMN1; SMN2GAAMAPTPOLB | |
| SCHEMBL14884740 | 0.80 | STAT3 (1.00) | STAT3SMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL25925010 | 0.77 | SMN1; SMN2 (0.53) | STAT3SMN1; SMN2PTGDR2MAPTPOLB | |
| SCHEMBL3275549 | 0.74 | PTGDR2 (0.70) | GAAPTGDR2MAPTPOLBALDH1A1 | |
| SCHEMBL3275553 | 0.74 | PTGDR2 (0.70) | GAAPTGDR2MAPTPOLBALDH1A1 | |
| SCHEMBL14564434 | 0.72 | KDM4E (0.47) | PTGDR2MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL7293153 | 0.72 | IMPDH2 (0.61) | SMN1; SMN2 | |
| SCHEMBL16709583 | 0.72 | PTGDR2 (0.50) | STAT3PTGDR2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | C9, C5, C1QBP | STAT3 2798/4885SMN1; SMN2 2279/4885GAA 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.