Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925383 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTRAB9APOLB | |
| SCHEMBL17023484 | 0.85 | KMT2A (0.49) | SMN1; SMN2LMNAHTTRAB9ARXFP1 | |
| SCHEMBL13539148 | 0.85 | LMNA (0.49) | SMN1; SMN2LMNAHTTRAB9APOLB | |
| SCHEMBL17023688 | 0.84 | CFD (0.49) | SMN1; SMN2LMNAKMT2ACREBBPALDH1A1 | |
| SCHEMBL29781757 | 0.84 | CFD (0.49) | SMN1; SMN2LMNAKMT2ACREBBPALDH1A1 | |
| SCHEMBL18572850 | 0.83 | LMNA (0.55) | SMN1; SMN2LMNAHTTRAB9APOLB | |
| SCHEMBL18554040 | 0.82 | PTGDR2 (0.47) | SMN1; SMN2LMNAHTTRAB9APOLB | |
| SCHEMBL12480373 | 0.82 | ALDH1A1 (0.56) | SMN1; SMN2LMNARAB9AKMT2ACREBBP | |
| SCHEMBL17053136 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHTTRAB9APOLB | |
| SCHEMBL12481690 | 0.81 | PTGDR2 (0.51) | SMN1; SMN2LMNARAB9APTGDR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | C9, C5, C1QBP | SMN1; SMN2 2279/4885LMNA 1451/4885HTT 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.