Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512259 | 0.73 | KDM4C (0.48) | SMN1; SMN2HPGDLMNA | |
| SCHEMBL21394609 | 0.72 | SMN1; SMN2 (0.44) | TDP2SMN1; SMN2BRD9LMNA | |
| SCHEMBL23134701 | 0.69 | BRD4 (0.70) | BRD9BRD4BRD2BRD7 | |
| SCHEMBL13588195 | 0.67 | SMN1; SMN2 (0.33) | SMN1; SMN2BRD9LMNA | |
| SCHEMBL7682628 | 0.67 | MAPT (0.46) | SMN1; SMN2MAPTKMT2AKDM4EHPGD | |
| SCHEMBL25865051 | 0.66 | BRD4 (0.48) | BRD9BRD4BRD2BRD7KDM4E | |
| SCHEMBL21394912 | 0.66 | SMN1; SMN2 (0.39) | TDP2SMN1; SMN2MAPTKMT2ABRD9 | |
| SCHEMBL23134699 | 0.66 | BRD4 (0.68) | BRD9BRD4BRD2BRD7 | |
| SCHEMBL22016864 | 0.65 | ALDH1A1 (0.41) | SMN1; SMN2BRD9BRD4KDM4EHPGD | |
| SCHEMBL24393050 | 0.65 | PDE10A (0.49) | TDP2SMN1; SMN2MAPTKMT2ABRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |