SCHEMBL2592579

SCHEMBL2592579

COc1ccc(C=O)cc1Oc1ccccc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.88
ALDH1A1 P00352 7/20 0.68
TSHR P16473 1/20 0.68
FDPS P14324 1/20 0.54
HPGD P15428 3/20 0.53
CYP1A2 P05177 2/20 0.53
AOX1 Q06278 1/20 0.53
CYP1A1 P04798 1/20 0.53
CYP1B1 Q16678 1/20 0.53
TRIM24 O15164 1/20 0.53
ALDH5A1 P51649 1/20 0.53
ABAT P80404 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TRIM33 Q9UPN9 1/20 0.53
ATM Q13315 1/20 0.51
MAPT P10636 4/20 0.49
HTT P42858 3/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1616189 0.93 TTR (1.00) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL31238528 0.93 TTR (1.00) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL11795573 0.90 TTR (0.81) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL29446607 0.90 TTR (0.81) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL21328349 0.89 TTR (0.69) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL7366005 0.86 ALDH1A1 (0.84) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL31070290 0.85 ALDH1A1 (0.66) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL9047353 0.84 ALDH1A1 (0.64) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL3993806 0.83 TTR (0.62) TTRALDH1A1TSHRFDPSHPGD
SCHEMBL17955067 0.83 TTR (0.81) TTRALDH1A1TSHRFDPSHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460855-A2 Oxygen scavenging compositions and packaging comprising said compositions Constar International Inc. (US) 2012-06-06 EP claimed
US-20090278087-A1 Oxygen Scavenging Compositions and Packaging Comprising Said Compositions CONSTAR INTERNATIONAL, INC (US) 2009-11-12 US claimed
EP-1848659-A2 OXYGEN SCAVENGING COMPOSITIONS AND PACKAGING COMPRISING SAID COMPOSITIONS Constar International Inc. (US) 2007-10-31 EP claimed
WO-2006088889-A2 OXYGEN SCAVENGING COMPOSITIONS AND PACKAGING COMPRISING SAID COMPOSITIONS CONSTAR INTERNATIONAL, INC. (US) 2006-08-24 WO claimed
US-20060180790-A1 polyesters; melt polymerization; packaging CONSTAR INTERNATIONAL INC. (US) 2006-08-17 US claimed
EP-3777979-B1 ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) 2024-01-17 EP disclosed
US-11440886-B2 Anti-inflammatory compound, and preparation and use thereof E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd. (CN) 2022-09-13 US disclosed
EP-3777979-A1 ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF Vivavision Biotech, Inc. (CN) 2021-02-17 EP disclosed
US-20200377460-A1 ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF VIVAVISION BIOTECH, INC. (CN) 2020-12-03 US disclosed
US-8980933-B2 Combretastatin analogs for use in the treatment of cancer UNIVERSITAT BAYREUTH (DE) 2015-03-17 US disclosed
EP-2566851-B1 Combretastatin analogs for use in the treatment of cancer UNIVERSITÄT BAYREUTH (DE) 2015-01-14 EP disclosed
US-8721920-B2 Oxygen scavenging compositions and packaging comprising said compositions PLASTIPAK PACKAGING, INC. (US) 2014-05-13 US disclosed
WO-2011138409-A1 COMBRETASTATIN ANALOGS FOR USE IN THE TREATMENT OF CANCER UNIVERSITÄT BAYREUTH (DE) 2011-11-10 WO disclosed
US-20100154361-A1 Oxygen Scavenging Compositions And Packaging Comprising Said Compositions CONSTAR INTERNATIONAL, INC. (US) 2010-06-24 US disclosed
US-7691290-B2 polyesters; melt polymerization; packaging CONSTAR INTERNATIONAL INC. (US) 2010-04-06 US disclosed
US-20090278087-A1 Oxygen Scavenging Compositions and Packaging Comprising Said Compositions CONSTAR INTERNATIONAL, INC (US) 2009-11-12 US disclosed
EP-1848659-A4 OXYGEN SCAVENGING COMPOSITIONS AND PACKAGING COMPRISING SAID COMPOSITIONS CONSTAR INT INC (US) 2009-08-12 EP disclosed
EP-1848659-A2 OXYGEN SCAVENGING COMPOSITIONS AND PACKAGING COMPRISING SAID COMPOSITIONS Constar International Inc. (US) 2007-10-31 EP disclosed
WO-2006088889-A2 OXYGEN SCAVENGING COMPOSITIONS AND PACKAGING COMPRISING SAID COMPOSITIONS CONSTAR INTERNATIONAL, INC. (US) 2006-08-24 WO disclosed
US-20060180790-A1 polyesters; melt polymerization; packaging CONSTAR INTERNATIONAL INC. (US) 2006-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440886-B2 Anti-inflammatory compound, and preparation and use thereof PDE4B, PDE4A, PDE7A TTR 4685/4885ALDH1A1 1382/4885TSHR 4371/4885
US-20090278087-A1 Oxygen Scavenging Compositions and Packaging Comprising Said Compositions LPO, GPX4, PRDX3 TTR 4281/4885ALDH1A1 548/4885TSHR 4668/4885
US-20200377460-A1 ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF PDE4B, PDE4A, PDE7A TTR 4685/4885ALDH1A1 1382/4885TSHR 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.