Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925529 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL25925570 | 0.85 | TSHR (0.36) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL25926241 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL6490246 | 0.79 | APEX1 (0.49) | ALDH1A1TSHRKMT2ALMNAHTT | |
| SCHEMBL6490243 | 0.79 | APEX1 (0.49) | ALDH1A1TSHRKMT2ALMNAHTT | |
| SCHEMBL29897709 | 0.79 | APEX1 (0.49) | ALDH1A1TSHRKMT2ALMNAHTT | |
| SCHEMBL29897705 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL6491185 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL6491181 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL6691845 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109513-A1 | USE OF AILDENAFIL OR SALT THEREOF IN PREPARATION OF MEDICINE FOR PREVENTING OR TREATING ISCHEMIC BRAIN DAMAGE | 真奥金银花药业有限公司 | 2023-06-22 | — | — | WO | disclosed |