Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691847 | 0.81 | LMNA (0.44) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL29897709 | 0.81 | APEX1 (0.49) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL6490246 | 0.81 | APEX1 (0.49) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL6490243 | 0.81 | APEX1 (0.49) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL6491185 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL6491181 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL29897705 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL25926241 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL25925529 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNANPC1HTT | |
| SCHEMBL4184668 | 0.75 | GPBAR1 (0.61) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400522-B1 | COMPOUNDS FOR TREATING IMPOTENCE | GUANGZHOU YOUCARE BIOPHARMACEATICS CO LTD (CN) | 2014-08-06 | — | — | EP | disclosed |
| EP-1400522-A1 | NEW COMPOUNDS FOR TREATING IMPOTENCE | Liu, Baoshun (CN) | 2004-03-24 | — | — | EP | disclosed |