SCHEMBL25926656

SCHEMBL25926656

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4oc5ccc(-c6ccc7oc8ccc(-n9c%10ccccc%10c%10ccccc%109)cc8c7c6)cc5c4c3)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 2/20 0.40
KDM4E B2RXH2 1/20 0.40
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
CHEK2 O96017 1/20 0.36
PLA2G10 O15496 1/20 0.36
PGR P06401 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
GAA P10253 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15248710 0.99 KDM4E (0.41) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL24216223 0.97 L3MBTL1 (0.40) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL20232388 0.97 KDM4E (0.40) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL25954243 0.96 PLA2G2A (0.38) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL25954241 0.96 PLA2G2A (0.38) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL24216961 0.96 PLA2G2A (0.38) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL24216264 0.96 PLA2G2A (0.39) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL15786052 0.96 ATM (0.39) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL22078722 0.96 ATM (0.39) L3MBTL1ATMKDM4EPLA2G2APLA2G4A
SCHEMBL21192088 0.96 CHEK2 (0.40) L3MBTL1ATMKDM4EPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-08-03 US disclosed
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE CRY1, PPOX, ORC3 L3MBTL1 1454/4885ATM 2148/4885KDM4E 2352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.