Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.52 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289625 | 0.96 | TSHR (0.56) | TSHRGNAI3GNAO1GNAI1FAAH | |
| SCHEMBL3955905 | 0.89 | TSHR (0.48) | TSHRGNAI3GNAO1GNAI1FAAH | |
| SCHEMBL3947828 | 0.85 | TSHR (0.42) | TSHRGNAI3GNAO1GNAI1FAAH | |
| SCHEMBL3952508 | 0.83 | PAOX (0.47) | TSHR | |
| SCHEMBL986238 | 0.82 | HRH3 (0.46) | TSHRGNAI3GNAO1GNAI1FAAH | |
| SCHEMBL984275 | 0.82 | HRH3 (0.46) | TSHRGNAI3GNAO1GNAI1FAAH | |
| SCHEMBL250855 | 0.82 | GNAI3 (0.70) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL6659463 | 0.82 | GNAI3 (0.62) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL1043043 | 0.82 | GNAI3 (0.70) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL35895 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688664-B2 | Modulators of fatty acid amide hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2017-06-27 | — | — | US | disclosed |
| US-20150099761-A1 | MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (US) | 2015-04-09 | — | — | US | disclosed |
| US-8940745-B2 | Modulators of fatty acid amide hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2015-01-27 | — | — | US | disclosed |
| EP-2566861-B1 | MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2014-05-14 | — | — | EP | disclosed |
| EP-2566861-A1 | MODULATORS OF FATTY ACID AMIDE HYDROLASE | Janssen Pharmaceutica, N.V. (BE) | 2013-03-13 | — | — | EP | disclosed |
| US-20130053398-A1 | MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (US) | 2013-02-28 | — | — | US | disclosed |
| WO-2011139951-A1 | MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099761-A1 | MODULATORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, APEH | TSHR 1808/4885GNAI3 1011/4885GNAO1 681/4885 |
| US-20130053398-A1 | MODULATORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, APEH | TSHR 1808/4885GNAI3 1011/4885GNAO1 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.