SCHEMBL2592758

SCHEMBL2592758

COC1=CC(=CN=NC=C2C=C(OC)C(=O)C(OC)=C2)C=C(OC)C1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 1/20 0.63
▸ HKDC1 Q2TB90 2/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ MEN1 O00255 2/20 0.56
▸ MAPT P10636 2/20 0.56
▸ MAPK1 P28482 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ USP2 O75604 1/20 0.56
▸ TP53 P04637 1/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ ALOX5 P09917 9/20 0.42
▸ PTGS2 P35354 5/20 0.42
▸ IDO1 P14902 1/20 0.39
▸ CDC25A P30304 1/20 0.39
▸ CDC25B P30305 1/20 0.39
▸ ERBB2 P04626 1/20 0.37
▸ PTPN1 P18031 1/20 0.35
▸ TEK Q02763 1/20 0.33
▸ POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoquinone SCHEMBL16556227 0.92 TYR (0.55) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL20176388 0.87 TYR (0.50) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL20437841 0.84 TYR (0.47) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL14280270 0.79 TYR (0.46) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL29684687 0.77 TYR (1.00) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL14306630 0.75 TYR (0.41) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL14280251 0.75 TYR (0.41) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL14280249 0.75 TYR (0.41) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL13780447 0.72 TYR (0.68) TYRHKDC1KDM4EMEN1MAPT
SCHEMBL197028 0.72 HKDC1 (0.70) TYRHKDC1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3894551-B1 POLYPEPTIDES HAVING XYLANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES AS (DK) 2026-04-22 — — EP disclosed
US-12385027-B2 Polypeptides having xylanase activity and polynucleotides encoding same NOVOZYMES A/S (DK) 2025-08-12 — — US disclosed
US-12385917-B2 Methods and compositions for tracking vegetation COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2025-08-12 — — US disclosed
US-20240271114-A1 CELLOBIOHYDROLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2024-08-15 — — US disclosed
EP-4410974-A2 CELLOBIOHYDROLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2024-08-07 — — EP disclosed
WO-2024137252-A1 PROCESS FOR REDUCING SYRUP VISCOSITY IN THE BACKEND OF A PROCESS FOR PRODUCING A FERMENTATION PRODUCT NOVOZYMES A/S (DK) 2024-06-27 — — WO disclosed
EP-3423577-B1 CELLOBIOHYDROLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES AS (DK) 2024-05-08 — — EP disclosed
EP-3227438-B1 LACCASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES AS (DK) 2024-03-27 — — EP disclosed
CN-107532154-B Polypeptides having cellobiohydrolase activity and polynucleotides encoding same 国投生物科技投资有限公司 2022-09-27 — — CN disclosed
EP-3433358-B1 CELLOBIOHYDROLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES AS (DK) 2022-07-06 — — EP disclosed
CN-108350044-B Polypeptides having cellobiohydrolase activity and polynucleotides encoding same 诺维信公司 2022-05-24 — — CN disclosed
US-20220064228-A1 Methods For Increasing The Productivity Of A Filamentous Fungal Cell In The Production Of A Polypeptide NOVOZYMES A/S (DK) 2022-03-03 — — US disclosed
EP-3052620-B1 PROCESSES FOR INCREASING ENZYMATIC HYDROLYSIS OF CELLULOSIC MATERIAL NOVOZYMES AS (DK) 2020-07-15 — — EP disclosed
WO-2017040907-A1 METHODS OF INHIBITING AA9 LYTIC POLYSACCHARIDE MONOOXYGENASE CATALYZED INACTIVATION OF ENZYME COMPOSITIONS NOVOZYMES A/S (DK) 2017-03-09 — — WO disclosed
US-20160298154-A1 Processes for Increasing Enzymatic Hydrolysis of Cellulosic Material NOVOZYMES A/S (DK) 2016-10-13 — — US disclosed
US-8454799-B2 Pulp composition for paper and solid board production BASF SE (DE) 2013-06-04 — — US disclosed
EP-2567024-A1 FIBROUS COMPOSITION FOR PAPER AND CARD PRODUCTION BASF SE (DE) 2013-03-13 — — EP disclosed
WO-2011138366-A1 FIBROUS COMPOSITION FOR PAPER AND CARD PRODUCTION BASF SE (DE) 2011-11-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220064228-A1 Methods For Increasing The Productivity Of A Filamentous Fungal Cell In The Production Of A Polypeptide ERG28, ETF1, RNGTT TYR 1416/4885HKDC1 4413/4885KDM4E 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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