Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280270 | 0.82 | TYR (0.46) | TYRMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14280244 | 0.80 | CYP19A1 (0.36) | GSK3BCYP19A1KMT2ASMN1; SMN2CYP1B1 | |
| SCHEMBL14306630 | 0.78 | TYR (0.41) | TYRMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14280245 | 0.78 | MEN1 (0.45) | TYRCYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14280256 | 0.77 | VCAM1 (0.41) | TYRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL18877782 | 0.76 | BRD4 (0.34) | CYP19A1KMT2ASMN1; SMN2CYP1B1BRD4 | |
| SCHEMBL2592758 | 0.75 | TYR (0.63) | TYRMEN1KMT2ASMN1; SMN2KDM4E | |
| Benzoquinone SCHEMBL16556227 | 0.69 | TYR (0.55) | TYRMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18877728 | 0.67 | PTGS2 (0.43) | GSK3BCYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10476855 | 0.67 | MAOA (0.51) | GSK3BMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314692-B2 | Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-01 | — | — | US | disclosed |
| US-7314692-B2 | Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-01 | — | — | US | disclosed |