Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20015030 | 0.89 | KDM4E (0.36) | ALDH1A1MEN1KMT2AKDM4ETAAR1 | |
| SCHEMBL11209771 | 0.79 | CD274 (0.41) | ALDH1A1KMT2AKDM4ESCN8ACTSA | |
| SCHEMBL6546985 | 0.78 | ESR1 (0.39) | RAB9AMEN1KMT2AESR1TAAR1 | |
| SCHEMBL6546213 | 0.78 | ESR1 (0.42) | ACHEMEN1KMT2AESR1TAAR1 | |
| SCHEMBL12446949 | 0.76 | GABRA1 (0.41) | ALDH1A1MEN1KMT2AKDM4ETAAR1 | |
| SCHEMBL21730322 | 0.73 | GABRA1 (0.39) | ALDH1A1TAAR1LMNAGABRA1GABRB2 | |
| SCHEMBL11209769 | 0.72 | DHFR (0.38) | RAB9AALDH1A1MEN1KMT2AESR1 | |
| SCHEMBL11203834 | 0.72 | MEN1 (0.33) | ALDH1A1MEN1KMT2AESR1CYP2D6 | |
| SCHEMBL6547626 | 0.71 | ADRA2A (0.42) | ALDH1A1MEN1KMT2AESR1TAAR1 | |
| SCHEMBL3970108 | 0.70 | GABRA1 (0.41) | RAB9AMEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219508-A1 | SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVE AND PRODRUG THEREOF | Shionogi & Co., Ltd (JP) | 2023-08-02 | — | — | EP | disclosed |