Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203115 | 0.87 | ALDH1A1 (0.69) | TDP1RXFP1CYP19A1ALDH1A1L3MBTL1 | |
| SCHEMBL219147 | 0.82 | KDM4E (0.66) | TDP1RXFP1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL345555 | 0.81 | RXFP1 (0.61) | TDP1RXFP1CYP19A1ALDH1A1L3MBTL1 | |
| SCHEMBL439393 | 0.80 | RXFP1 (0.74) | TDP1RXFP1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL2135316 | 0.80 | F2 (0.73) | TDP1RXFP1F2PRSS1PRSS2 | |
| SCHEMBL166821 | 0.80 | MAPT (0.67) | TDP1RXFP1ALDH1A1RAB9ANPC1 | |
| SCHEMBL19501001 | 0.80 | NPC1 (0.67) | TDP1RXFP1ALDH1A1RAB9ANPC1 | |
| Dimethylamine SCHEMBL10625504 | 0.79 | KDM4E (0.61) | TDP1RXFP1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL7800028 | 0.79 | TDP1 (0.66) | TDP1RXFP1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL17299114 | 0.79 | RXFP1 (0.62) | TDP1RXFP1CYP19A1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265514-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2023-08-02 | — | — | EP | disclosed |