SCHEMBL345555

SCHEMBL345555

C=C(C)C(=O)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.61
PTPN11 Q06124 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 3/20 0.50
EPHX2 P34913 1/20 0.50
NR1H4 Q96RI1 1/20 0.50
PKM P14618 1/20 0.49
MITF O75030 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP19A1 P11511 2/20 0.47
FFAR1 O14842 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CA12 O43570 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439393 0.88 RXFP1 (0.74) RXFP1TDP1ALDH1A1NR1H4MEN1
SCHEMBL7800028 0.86 TDP1 (0.66) RXFP1TDP1ALDH1A1MEN1KMT2A
SCHEMBL17299114 0.86 RXFP1 (0.62) RXFP1TDP1ALDH1A1MEN1KMT2A
SCHEMBL15213831 0.84 ALDH1A1 (0.53) PTPN11TDP1ALDH1A1EPHX2NR1H4
SCHEMBL203115 0.84 ALDH1A1 (0.69) RXFP1TDP1ALDH1A1MEN1KMT2A
SCHEMBL24799884 0.83 RXFP1 (0.59) RXFP1TDP1ALDH1A1MEN1KMT2A
SCHEMBL16866619 0.83 RXFP1 (0.59) RXFP1TDP1ALDH1A1MEN1KMT2A
SCHEMBL17084525 0.82 RXFP1 (0.67) RXFP1PTPN11TDP1ALDH1A1NR1H4
Acedoben SCHEMBL11793874 0.82 ALDH1A1 (0.66) PTPN11TDP1ALDH1A1EPHX2NR1H4
SCHEMBL219147 0.82 KDM4E (0.66) RXFP1TDP1ALDH1A1EPHX2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 587 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US claimed
EP-4312947-A1 SELF-ADHESIVE FISSURE SEALANT Kulzer GmbH (DE) 2024-02-07 EP claimed
CN-113224242-A Organic solar cell preparation method for improving shape thermal stability of active layer 天津大学 2021-08-06 CN claimed
CN-103668130-A Preparation method of metal nanostructure ZHOU MINGJIE 2014-03-26 CN claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
US-7824840-B2 polymeric binder provides the post-development bakeability of imaged elements while increasing imaging sensitivity (speed) and maintaining resistance to press chemicals; solvent resistance; lithographic printing plates EASTMAN KODAK COMPANY (US) 2010-11-02 US claimed
US-20090118460-A1 SOLUBLE AROMATIC RANDOM COPOLYIMIDE AND PROCESS FOR PREPARING SAME LAURENTIAN UNIVERSITY (CA) 2009-05-07 US claimed
US-20090042135-A1 polymeric binder provides the post-development bakeability of imaged elements while increasing imaging sensitivity (speed) and maintaining resistance to press chemicals; solvent resistance; lithographic printing plates BANK OF AMERICA, N.A., AS AGENT 2009-02-12 US claimed
US-7300726-B1 to improve the post-development bakeability of imaged elements while increasing imaging sensitivity (speed) and maintaining resistance to press chemicals; lithographic printing plates EASTMAN KODAK COMPANY (US) 2007-11-27 US claimed
US-7115674-B2 Dental self-curing resin cement compositions DENTKIST, INC. (KR) 2006-10-03 US claimed
US-6869741-B2 Electrophotographic photoreceptors with novel overcoats SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-03-22 US claimed
US-20050049326-A1 Dental self-curing resin cement compositions DENTKIST, INC. (KR) 2005-03-03 US claimed
US-20040176496-A1 Light-curing dental adhesive compositions DENTKIST, INC. (KR) 2004-09-09 US claimed
US-5871894-A CONTAINING CYAN DYE-FORMING COUPLER AND ADDITION COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1999-02-16 US claimed
EP-0881535-A1 Silver halide color photographic light-sensitive material Fuji Photo Film Co., Ltd. (JP) 1998-12-02 EP claimed
US-4699867-A Radiation-sensitive positive working composition and material with aqueous-alkaline soluble acryamide or methacryamide copolymer having hydroxyl or carboxyl groups HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-13 US claimed
EP-4568954-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASE (CDK) 12 AND/OR CDK13 AND USES THEREOF Insilico Medicine IP Limited (HK) 2025-06-18 EP disclosed
CN-119677729-A Cyclin Dependent Kinase (CDK) 12 and/or CDK13 inhibitors and uses thereof 英矽智能科技知识产权有限公司 2025-03-21 CN disclosed
US-4699867-A Radiation-sensitive positive working composition and material with aqueous-alkaline soluble acryamide or methacryamide copolymer having hydroxyl or carboxyl groups HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-13 US disclosed
US-4130702-A Polyacryloylaminobenzoic acid, polymethacryloylaminobenzoic acid and method of preparation CELANESE CORPORATION (US) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176496-A1 Light-curing dental adhesive compositions HBG2, GRIN2A, HBG1 RXFP1 4802/4885PTPN11 4878/4885TDP1 3235/4885
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS RXFP1 3770/4885PTPN11 4795/4885TDP1 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.