Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231117 | 0.90 | HPGD (0.41) | KCNJ1KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL19254702 | 0.86 | CYP2A6 (0.44) | KCNJ1KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL25929341 | 0.81 | KCNJ1 (0.34) | KCNJ1KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL7658751 | 0.81 | KMT2A (0.36) | KCNJ1KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL1606027 | 0.81 | ALDH1A1 (0.39) | KCNJ1KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL12107913 | 0.77 | CNR1 (0.41) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL12113863 | 0.77 | CTSK (0.42) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL14675722 | 0.75 | SKP2 (0.44) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL12844147 | 0.75 | TRPV4 (0.40) | CNR1CNR2ALDH1A1CTSSCTSK | |
| SCHEMBL11321401 | 0.75 | CNR1 (0.58) | CNR1CNR2KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |