Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18045604 | 0.99 | GPR35 (0.33) | DPP4GPR35HIF1AEPAS1TP53 | |
| SCHEMBL12913130 | 0.99 | GPR35 (0.33) | DPP4GPR35HIF1AEPAS1TP53 | |
| SCHEMBL18090330 | 0.97 | DPP4 (0.32) | DPP4GPR35HIF1AEPAS1 | |
| SCHEMBL16705790 | 0.95 | GPR35 (0.31) | GPR35HIF1AEPAS1 | |
| SCHEMBL15724556 | 0.95 | GPR35 (0.31) | GPR35HIF1AEPAS1 | |
| SCHEMBL12913160 | 0.94 | DPP4 (0.33) | DPP4ALDH1A1 | |
| SCHEMBL13410220 | 0.90 | MEN1 (0.32) | GPR35TP53CYP3A4ALOX15TSHR | |
| SCHEMBL18045595 | 0.90 | DPP4 (0.39) | DPP4GPR35HIF1AEPAS1CYP3A4 | |
| SCHEMBL13410257 | 0.89 | MEN1 (0.31) | GPR35TP53CYP3A4ALOX15TSHR | |
| SCHEMBL26088965 | 0.86 | DPP4 (0.40) | DPP4GPR35HIF1AEPAS1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018397-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2015-04-28 | — | — | US | disclosed |
| US-9018397-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2015-04-28 | — | — | US | disclosed |
| EP-2209788-B1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-20130172575-A1 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-07-04 | — | — | US | disclosed |
| US-20130172575-A1 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-07-04 | — | — | US | disclosed |
| US-8441002-B2 | Organic semiconductor composite, organic transistor material and organic field effect transistor | TORAY INDUSTRIES, INC. (JP) | 2013-05-14 | — | — | US | disclosed |
| US-8404864-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8404864-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| EP-2566848-A1 | IMPROVED OLIGOTHIOPHENES | Commonwealth Scientific and Industrial Research Organisation (AU) | 2013-03-13 | — | — | EP | disclosed |
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
| WO-2011137487-A1 | IMPROVED OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011137487-A1 | IMPROVED OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2011-11-10 | — | — | WO | disclosed |
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20100102299-A1 | ORGANIC SEMICONDUCTOR COMPOSITE, ORGANIC TRANSISTOR MATERIAL AND ORGANIC FIELD EFFECT TRANSISTOR | TORAY INDUSTRIES, INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| WO-2009047104-A2 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (CH) | 2009-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | PPOX, PIN1, DDT | DPP4 2935/4885GPR35 3943/4885HIF1A 4361/4885 |
| US-20130042918-A1 | OLIGOTHIOPHENES | NR0B2, NR2C2, NR1H2 | DPP4 4832/4885GPR35 199/4885HIF1A 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.