Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927711 | 0.83 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9APOLBPIK3CD | |
| SCHEMBL25134014 | 0.83 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9APOLBPIK3CD | |
| SCHEMBL26648895 | 0.78 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9APOLBPIK3CD | |
| SCHEMBL24320368 | 0.75 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9APOLBPIK3CD | |
| SCHEMBL21876734 | 0.71 | PDE4D (0.38) | ALDH1A1PRKDCLGMNMAPT | |
| SCHEMBL21876680 | 0.71 | HTR6 (0.39) | ALDH1A1NPC1RAB9ALGMNMAPT | |
| SCHEMBL21876628 | 0.70 | OPRK1 (0.39) | ALDH1A1NPC1RAB9ALGMNMAPT | |
| SCHEMBL27123984 | 0.70 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9APOLBPKM | |
| SCHEMBL26969658 | 0.70 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9APOLBPKM | |
| SCHEMBL24319781 | 0.69 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9APOLBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |