Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 7/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983556 | 0.83 | ALDH1A1 (0.61) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3059596 | 0.80 | MEN1 (0.47) | MEN1ALDH1A1KMT2AGNAI3GNAO1 | |
| SCHEMBL985369 | 0.79 | MEN1 (0.46) | MEN1ALDH1A1KMT2AGNAI3GNAO1 | |
| SCHEMBL985368 | 0.79 | MEN1 (0.46) | MEN1ALDH1A1KMT2AGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL17796058 | 0.79 | GNAI3 (0.46) | MEN1ALDH1A1KMT2AGNAI3GNAO1 | |
| SCHEMBL17287129 | 0.78 | MMP1 (0.41) | MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL985143 | 0.77 | GNAI3 (0.45) | MEN1ALDH1A1KMT2AGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL985144 | 0.77 | GNAI3 (0.45) | MEN1ALDH1A1KMT2AGNAI3GNAO1 | |
| SCHEMBL13866419 | 0.76 | MMP1 (0.44) | ALDH1A1DPP4EPHX2DPP7 | |
| SCHEMBL10280581 | 0.76 | MEN1 (0.43) | MEN1ALDH1A1KMT2AGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | KRAS, HRAS, NRAS | MEN1 2804/4885ALDH1A1 2792/4885KMT2A 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.