Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975788 | 0.90 | KMT2A (0.45) | LMNATSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23975860 | 0.90 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2ADORA3KMT2AMEN1 | |
| SCHEMBL30118615 | 0.90 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2ADORA3KMT2AMEN1 | |
| SCHEMBL23986833 | 0.89 | ADORA3 (0.42) | LMNASMN1; SMN2ADORA3KMT2AMEN1 | |
| SCHEMBL23976024 | 0.87 | PDE10A (0.44) | LMNATSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30118764 | 0.87 | ADORA3 (0.40) | LMNATSHRSMN1; SMN2ADORA3KMT2A | |
| SCHEMBL23975871 | 0.87 | ADORA3 (0.40) | LMNATSHRSMN1; SMN2ADORA3KMT2A | |
| SCHEMBL25939854 | 0.85 | PDE3B (0.36) | LMNATSHRSMN1; SMN2ADORA3KMT2A | |
| SCHEMBL23976225 | 0.84 | MEN1 (0.37) | ADORA3KMT2AMEN1POLBKDM4E | |
| SCHEMBL23976757 | 0.84 | ADORA3 (0.36) | LMNATSHRSMN1; SMN2ADORA3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226074-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226074-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | SLC40A1, HAMP, SLC19A1 | LMNA 1425/4885TSHR 2368/4885SMN1; SMN2 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.