SCHEMBL25937022

SCHEMBL25937022

c1cnc2[nH]c(-c3cnc4[nH]cnc4c3)cc2c1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 19/20 0.54
CCNB2 O95067 1/20 0.50
CDK1 P06493 1/20 0.50
CCNB1 P14635 1/20 0.50
CCNB3 Q8WWL7 1/20 0.50
WNT1 P04628 1/20 0.44
CLK2 P49760 1/20 0.44
CLK3 P49761 1/20 0.44
DYRK1A Q13627 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19654537 0.81 RIPK1 (0.57) RIPK1CCNB2CDK1CCNB1CCNB3
SCHEMBL21191525 0.80 RIPK1 (0.36) RIPK1CCNB2CDK1CCNB1CCNB3
SCHEMBL25942800 0.76 RIPK1 (0.48) RIPK1CCNB2CDK1CCNB1CCNB3
SCHEMBL16321934 0.75 RIPK1 (0.62) RIPK1CCNB2CDK1CCNB1CCNB3
SCHEMBL29424136 0.75 QPCT (0.59) DYRK1A
SCHEMBL1780991 0.74 CYP19A1 (0.66) RIPK1CCNB2CDK1CCNB1CCNB3
SCHEMBL1778505 0.74 RIPK1 (0.74) RIPK1CCNB2CDK1CCNB1CCNB3
SCHEMBL28135193 0.72 DAO (0.42) RIPK1CCNB2CDK1CCNB1CCNB3
SCHEMBL26053438 0.72 RIPK1 (0.71) RIPK1CCNB2CDK1CCNB1CCNB3
SCHEMBL21076176 0.72 CYP19A1 (0.34) CLK2CLK3DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250112-A1 ORGANIC COMPOUNDS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250112-A1 ORGANIC COMPOUNDS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD AOX1, AOC2, OR10J3 RIPK1 3618/4885CCNB2 931/4885CDK1 1390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.