Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 12/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12333 | 0.85 | DAO (0.53) | DAORIPK1CCNB2CDK1CCNB1 | |
| SCHEMBL29431626 | 0.80 | — | — | |
| SCHEMBL10759 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL8971987 | 0.78 | MAPK1 (0.46) | AXLNUDT1MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL29424070 | 0.78 | MAPK1 (0.46) | AXLNUDT1MAPTALDH1A1KDM4E | |
| SCHEMBL2446692 | 0.78 | MAPK1 (0.46) | AXLNUDT1MAPTALDH1A1KDM4E | |
| SCHEMBL25942800 | 0.74 | RIPK1 (0.48) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL25937022 | 0.72 | RIPK1 (0.54) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| Formic Acid SCHEMBL29774382 | 0.70 | KMT2A (0.42) | DAOAXLNUDT1ALDH1A1KDM4E | |
| Triphosphate SCHEMBL28137708 | 0.70 | DAO (0.46) | DAORIPK1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104093715-B | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives | 埃科特莱茵药品有限公司 | 2017-04-26 | — | — | CN | disclosed |