Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557526 | 1.00 | ALDH1A1 (0.60) | ALDH1A1POLBKDM4ECASP3CASP2 | |
| SCHEMBL25937359 | 0.89 | DDB1 (0.48) | ALDH1A1POLBKDM4ECASP3CASP2 | |
| SCHEMBL25429434 | 0.82 | ALDH1A1 (0.71) | ALDH1A1POLBKDM4ECASP3CASP2 | |
| SCHEMBL7997935 | 0.80 | SMN1; SMN2 (0.61) | ALDH1A1CASP3CASP2KMT2AMEN1 | |
| SCHEMBL24335866 | 0.75 | CASP3 (0.72) | ALDH1A1POLBKDM4ECASP3CASP2 | |
| SCHEMBL25430532 | 0.75 | CASP3 (0.76) | ALDH1A1KDM4ECASP3CASP2KMT2A | |
| SCHEMBL24335860 | 0.74 | TSHR (0.68) | ALDH1A1POLBKDM4ECASP3CASP2 | |
| SCHEMBL29580481 | 0.74 | TSHR (0.68) | ALDH1A1POLBKDM4ECASP3CASP2 | |
| SCHEMBL30557602 | 0.74 | NOTUM (0.56) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL11035331 | 0.73 | CASP3 (1.00) | ALDH1A1POLBKDM4ECASP3CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |