Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937565 | 0.89 | KCNQ2 (0.40) | SIGMAR1MEN1ALDH1A1KMT2AKCNQ2 | |
| SCHEMBL25937545 | 0.89 | KCNQ2 (0.46) | SIGMAR1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL30557580 | 0.89 | KCNQ2 (0.46) | SIGMAR1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL25937866 | 0.85 | TP53 (0.40) | SIGMAR1EGFRRORC | |
| SCHEMBL25937457 | 0.83 | GRM7 (0.47) | SIGMAR1L3MBTL1CTSL | |
| SCHEMBL25430814 | 0.83 | MAPT (0.39) | MEN1KMT2AKCNQ2AGTR2EGFR | |
| SCHEMBL25937580 | 0.82 | SIGMAR1 (0.40) | SIGMAR1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL25937403 | 0.82 | KCNQ2 (0.41) | SIGMAR1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL25937779 | 0.77 | KDR (0.43) | SIGMAR1MEN1KMT2AMMP1MMP9 | |
| SCHEMBL25937424 | 0.76 | NOTUM (0.53) | SIGMAR1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |