Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 9/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488379 | 0.93 | QPCT (0.42) | QPCTEPHX1EPHX2CDK2FLT4 | |
| SCHEMBL20488757 | 0.88 | QPCT (0.39) | QPCT | |
| SCHEMBL25940616 | 0.82 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C19L3MBTL1MAPT | |
| SCHEMBL20488749 | 0.77 | RAB9A (0.38) | ALDH1A1CYP1A2CYP2C19RAB9AL3MBTL1 | |
| SCHEMBL20488754 | 0.76 | HPGD (0.37) | EPHX2ALDH1A1CYP1A2CYP2C19RAB9A | |
| SCHEMBL20487852 | 0.75 | HPGD (0.38) | ALDH1A1CYP1A2CYP2C19L3MBTL1MAPT | |
| SCHEMBL20488746 | 0.75 | ACHE (0.35) | — | |
| SCHEMBL20487891 | 0.73 | HPGD (0.35) | EPHX2ALDH1A1CYP1A2CYP2C19RAB9A | |
| SCHEMBL29854881 | 0.73 | HPGD (0.34) | EPHX2ALDH1A1CYP1A2CYP2C19RAB9A | |
| SCHEMBL26137038 | 0.73 | GAA (0.43) | QPCTALDH1A1CYP1A2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718626-B2 | Macrocyclic compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718626-B2 | Macrocyclic compounds for treatment of medical disorders | CFD, TFPI, CFH | QPCT 1565/4885EPHX1 1257/4885EPHX2 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.