Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.43 |
| ▸ | TNKS | O95271 | 3/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30136015 | 1.00 | PARP1 (0.43) | PARP1TNKSTNKS2SCD5TACR1 | |
| SCHEMBL30830739 | 0.95 | PARP1 (0.42) | PARP1TNKSTNKS2SCD5TACR1 | |
| SCHEMBL25035220 | 0.95 | CYP11B2 (0.42) | PARP1TNKSTNKS2SCD5PRMT5 | |
| SCHEMBL31018307 | 0.95 | CYP11B2 (0.42) | PARP1TNKSTNKS2SCD5PRMT5 | |
| SCHEMBL25935411 | 0.92 | PARP1 (0.43) | PARP1TNKSTNKS2SCD5TACR1 | |
| SCHEMBL26642195 | 0.91 | TLR9 (0.46) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30135873 | 0.87 | OPRD1 (0.40) | PRMT5CNR2OPRD1OPRK1GPR119 | |
| SCHEMBL30830629 | 0.87 | CYP3A4 (0.48) | SCD5PRMT5CYP11B2OPRD1OPRK1 | |
| SCHEMBL25819356 | 0.87 | CYP11B2 (0.42) | PARP1TNKSTNKS2SCD5PRMT5 | |
| SCHEMBL30831067 | 0.87 | HSD17B10 (0.51) | SCD5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242541-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242541-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | PLK1, BUB1B, BUB1 | PARP1 221/4885TNKS 115/4885TNKS2 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.