Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25947315 | 0.96 | TSHR (0.41) | PKMTSHRCASP3MAPTNPSR1 | |
| SCHEMBL25947900 | 0.96 | PKM (0.44) | PKMTSHRCASP3MAPTNPSR1 | |
| SCHEMBL25947211 | 0.93 | PKM (0.42) | PKMTSHRCASP3MAPTNPSR1 | |
| SCHEMBL25949793 | 0.90 | PKM (0.44) | PKMTSHRCASP3MAPTNPSR1 | |
| SCHEMBL25939844 | 0.88 | PKM (0.40) | PKMTSHRCASP3MAPTNPSR1 | |
| SCHEMBL25951709 | 0.87 | PKM (0.39) | PKMTSHRCASP3MAPTNPSR1 | |
| SCHEMBL25947610 | 0.86 | TSHR (0.42) | PKMTSHRCASP3MAPTALOX5 | |
| SCHEMBL25949845 | 0.86 | PKM (0.45) | PKMTSHRCASP3MAPTNPSR1 | |
| SCHEMBL25947077 | 0.84 | TSHR (0.44) | PKMTSHRCASP3MAPTALOX5 | |
| SCHEMBL25947856 | 0.83 | TSHR (0.49) | PKMTSHRMAPTNPSR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |