Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ODC1 | P11926 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454707 | 0.81 | DGAT1 (0.34) | DGAT1THRBPKMHTTODC1 | |
| SCHEMBL16411264 | 0.80 | DGAT1 (0.33) | DGAT1THRBPKMHTTODC1 | |
| SCHEMBL28165431 | 0.74 | ITGB3 (0.34) | DGAT1ODC1 | |
| Hydrochloric Acid SCHEMBL2543241 | 0.74 | NAALAD2 (0.39) | HRH4HRH3ODC1 | |
| SCHEMBL7389000 | 0.73 | MEN1 (0.45) | CTSK | |
| SCHEMBL9073508 | 0.73 | MEN1 (0.45) | CTSK | |
| SCHEMBL30169556 | 0.71 | DGAT1 (0.34) | DGAT1THRBODC1 | |
| SCHEMBL30496007 | 0.71 | LTA4H (0.35) | — | |
| SCHEMBL15415012 | 0.71 | DGAT1 (0.36) | DGAT1THRBODC1 | |
| SCHEMBL17077599 | 0.70 | AKT1 (0.33) | THRBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571496-A1 | CONTROLLED DRUG RELEASE FROM DENDRIMERS | Prolynx Llc (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011140376-A1 | CONTROLLED DRUG RELEASE FROM DENDRIMERS | PROLYNX LLC (US) | 2011-11-10 | — | — | WO | disclosed |