Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ODC1 | P11926 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16411264 | 0.86 | DGAT1 (0.33) | DGAT1THRBPKMHTTODC1 | |
| SCHEMBL2595290 | 0.81 | CA14 (0.35) | DGAT1THRBPKMHTTODC1 | |
| SCHEMBL16731997 | 0.81 | TDP1 (0.53) | HTTMEN1GAAKMT2A | |
| SCHEMBL28165431 | 0.80 | ITGB3 (0.34) | DGAT1ODC1ITGB3ITGA2B | |
| SCHEMBL16731989 | 0.79 | MEN1 (0.51) | HTTMEN1GAAKMT2A | |
| SCHEMBL30169556 | 0.77 | DGAT1 (0.34) | DGAT1THRBODC1MEN1GAA | |
| SCHEMBL15415012 | 0.76 | DGAT1 (0.36) | DGAT1THRBODC1MEN1KMT2A | |
| SCHEMBL4617700 | 0.76 | ODC1 (0.37) | DGAT1THRBODC1MEN1KMT2A | |
| SCHEMBL4617707 | 0.76 | ODC1 (0.37) | DGAT1THRBODC1MEN1KMT2A | |
| SCHEMBL28914719 | 0.76 | ODC1 (0.37) | DGAT1THRBODC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4203968-A1 | DENDRIMER-DRUG CONJUGATE | Starpharma Pty Limited (AU) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022040761-A1 | DENDRIMER-DRUG CONJUGATE | STARPHARMA PTY LTD (AU) | 2022-03-03 | — | — | WO | disclosed |