Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15862314 | 0.82 | SLC6A2 (0.47) | SLC6A2P2RX7MEN1KMT2APOLB | |
| SCHEMBL18530068 | 0.79 | SLC6A2 (0.47) | SLC6A2P2RX7MEN1KMT2APOLB | |
| SCHEMBL1536298 | 0.75 | GRM2 (0.35) | — | |
| SCHEMBL10272322 | 0.73 | CETP (0.54) | SLC6A2MEN1KMT2APOLBNAPRT | |
| SCHEMBL307697 | 0.73 | SLC6A2 (0.48) | SLC6A2P2RX7MEN1KMT2APOLB | |
| SCHEMBL31552469 | 0.69 | P2RX7 (0.60) | SLC6A2P2RX7MEN1KMT2ANPSR1 | |
| SCHEMBL4401208 | 0.69 | ALDH1A1 (0.44) | P2RX7MEN1KMT2APOLBGAA | |
| SCHEMBL371986 | 0.69 | ALDH1A1 (0.44) | P2RX7MEN1KMT2APOLBGAA | |
| SCHEMBL10965027 | 0.69 | TGM2 (0.42) | SLC6A2P2RX7MEN1KMT2APOLB | |
| SCHEMBL10202348 | 0.68 | SPHK1 (0.48) | SLC6A2MEN1KMT2APOLBNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137342-A1 | CYCLOPROPYL DICARBOXAMIDES AND ANALOGS EXHIBITING ANTI-CANCER AND ANTI-PROLIFERATIVE ACTIVITES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2011-11-03 | — | — | WO | disclosed |