Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | GLS | O94925 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588098 | 0.87 | GPR119 (0.44) | GPR119GLSEPHX1KDM4EMAPT | |
| SCHEMBL15312974 | 0.87 | GPR119 (0.44) | GPR119GLSEPHX1KDM4EMAPT | |
| SCHEMBL15313014 | 0.84 | PIM1 (0.37) | KDM4EMAPTHPGDFAAHLMNA | |
| SCHEMBL1043606 | 0.83 | HPGD (0.49) | GPR119EPHX1KDM4EMAPTTHRB | |
| SCHEMBL28788513 | 0.82 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL419123 | 0.82 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL1774510 | 0.82 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL1120132 | 0.82 | GPR119 (0.47) | GPR119EPHX1KDM4EMAPTTHRB | |
| SCHEMBL13422175 | 0.82 | EPHX1 (0.55) | GPR119EPHX1KDM4ETHRBLMNA | |
| SCHEMBL15717626 | 0.82 | GPR119 (0.52) | GPR119KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563786-B1 | Ketoheteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-9357779-B2 | Ketoheteroarylpiperdine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-07 | — | — | US | disclosed |
| US-9220266-B2 | Ketoheteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| US-20130274292-A1 | Ketoheteroarylpiperdine and -Piperazine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-10-17 | — | — | US | disclosed |
| CN-102971314-A | Ketoheteroarylpiperidine and ketoheteroarylpiperazine derivates as fungicides | BAYER CROPSCIENCE AG | 2013-03-13 | — | — | CN | disclosed |
| EP-2563786-A1 | KETOHETEROARYLPIPERIDINE AND KETOHETEROARYLPIPERAZINE DERIVATES AS FUNGICIDES | Bayer CropScience AG (DE) | 2013-03-06 | — | — | EP | disclosed |
| US-20110312999-A1 | Ketoheteroarylpiperidine and -Piperazine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | US | disclosed |
| WO-2011134969-A1 | KETOHETEROARYLPIPERIDINE AND KETOHETEROARYLPIPERAZINE DERIVATES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274292-A1 | Ketoheteroarylpiperdine and -Piperazine Derivatives as Fungicides | CYP4Z1, CYP51A1, CYP1A1 | GPR119 355/4885GLS 675/4885EPHX1 605/4885 |
| US-20110312999-A1 | Ketoheteroarylpiperidine and -Piperazine Derivatives as Fungicides | CYP4Z1, CYP51A1, KCNH1 | GPR119 1043/4885GLS 488/4885EPHX1 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.