Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | DNM1L | O00429 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595508 | 0.84 | GPR119 (0.47) | KDM4EHPGDFAAHLMNAMAPT | |
| SCHEMBL15312962 | 0.83 | BAZ2A (0.34) | PIM1PIM3PIM2BAZ2ADNM1L | |
| SCHEMBL15312959 | 0.83 | BAZ2A (0.34) | PIM1PIM3PIM2BAZ2ADNM1L | |
| SCHEMBL3454398 | 0.83 | USP30 (0.42) | PIM1PIM3PIM2DNM1LSMN1; SMN2 | |
| SCHEMBL2952296 | 0.81 | CASP8 (0.42) | ALDH1A1HSD17B10SPRFAAHHTT | |
| Hydrochloric Acid SCHEMBL2594203 | 0.81 | BAZ2A (0.43) | PIM1PIM3PIM2BAZ2ADNM1L | |
| SCHEMBL1045160 | 0.80 | HTR2C (0.44) | ALDH1A1KDM4EHSD17B10HPGDSPR | |
| SCHEMBL2591277 | 0.79 | ALDH1A1 (0.33) | PIM1PIM3PIM2DNM1LALDH1A1 | |
| SCHEMBL1884435 | 0.79 | FAAH (0.38) | PIM1PIM3PIM2SMOFAAH | |
| SCHEMBL1773857 | 0.78 | BAZ2A (0.40) | BAZ2ASPRFAAHTRPC3TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9357779-B2 | Ketoheteroarylpiperdine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-07 | — | — | US | disclosed |
| US-9220266-B2 | Ketoheteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| US-20130274292-A1 | Ketoheteroarylpiperdine and -Piperazine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20110312999-A1 | Ketoheteroarylpiperidine and -Piperazine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274292-A1 | Ketoheteroarylpiperdine and -Piperazine Derivatives as Fungicides | CYP4Z1, CYP51A1, CYP1A1 | PIM1 722/4885PIM3 1390/4885PIM2 914/4885 |
| US-20110312999-A1 | Ketoheteroarylpiperidine and -Piperazine Derivatives as Fungicides | CYP4Z1, CYP51A1, KCNH1 | PIM1 672/4885PIM3 1193/4885PIM2 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.