Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384299 | 0.81 | ALDH1A1 (0.38) | CHRM1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12633371 | 0.77 | GABRP (0.43) | CHRM1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13770949 | 0.77 | CHRNB2 (0.46) | CHRM1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22912887 | 0.76 | USP2 (0.36) | CHRM1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7942491 | 0.74 | CHRM1 (0.48) | CHRM1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL6753704 | 0.74 | CHRM1 (0.38) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL13780656 | 0.74 | ALDH1A1 (0.38) | CHRM1CHRNB2CHRNA4 | |
| SCHEMBL23153529 | 0.73 | CHRM1 (0.35) | CHRM1 | |
| SCHEMBL17789614 | 0.73 | NOS3 (0.39) | CHRM1CHRNB2CHRNB4CHRNA4USP2 | |
| SCHEMBL14280513 | 0.72 | CHRM1 (0.32) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223753-A1 | AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2023-08-09 | — | — | EP | disclosed |