Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25959315 | 0.96 | SCN9A (0.41) | PCSK9SCN9ACNR2VNN1ALOX5AP | |
| SCHEMBL25958904 | 0.88 | ALDH1A1 (0.37) | SCN9ACNR2VNN1LRRK2 | |
| SCHEMBL25959270 | 0.84 | SCN9A (0.40) | SCN9ACNR2VNN1LRRK2IRAK4 | |
| SCHEMBL25959288 | 0.84 | VNN1 (0.41) | SCN9ACNR2VNN1LRRK2RORC | |
| SCHEMBL25958987 | 0.83 | LRRK2 (0.41) | SCN9AVNN1LRRK2RORC | |
| SCHEMBL25960484 | 0.80 | KMT2A (0.36) | IRAK4 | |
| SCHEMBL25957156 | 0.80 | ALDH1A1 (0.41) | — | |
| SCHEMBL25958758 | 0.78 | ALOX5AP (0.38) | PCSK9ALOX5APFEN1TRPC6 | |
| SCHEMBL25960670 | 0.77 | IRAK4 (0.36) | IRAK4 | |
| SCHEMBL25960881 | 0.75 | PCSK9 (0.34) | PCSK9CNR2LRRK2TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870582-B1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2023-07-19 | — | — | EP | disclosed |