Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25958987 | 0.85 | LRRK2 (0.41) | VNN1LRRK2SMN1; SMN2FLT3RORC | |
| SCHEMBL25959229 | 0.84 | PCSK9 (0.39) | VNN1LRRK2CNR2RORCSCN9A | |
| SCHEMBL25961687 | 0.82 | VNN1 (0.39) | VNN1LRRK2HPGD | |
| SCHEMBL25959308 | 0.82 | LRRK2 (0.36) | VNN1LRRK2SMN1; SMN2CNR2RORC | |
| SCHEMBL25957627 | 0.82 | VNN1 (0.35) | VNN1LRRK2 | |
| SCHEMBL25957185 | 0.82 | VNN1 (0.38) | VNN1SMN1; SMN2TSHR | |
| SCHEMBL25957181 | 0.81 | VNN1 (0.36) | VNN1LRRK2 | |
| SCHEMBL25958792 | 0.81 | VNN1 (0.40) | VNN1SMN1; SMN2HPGDTSHRESR2 | |
| SCHEMBL25959315 | 0.80 | SCN9A (0.41) | VNN1LRRK2CNR2SCN9A | |
| SCHEMBL25958904 | 0.80 | ALDH1A1 (0.37) | VNN1LRRK2CNR2SCN9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870582-B1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2023-07-19 | — | — | EP | disclosed |