Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.30 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25958662 | 0.82 | SMN1; SMN2 (0.45) | VNN1SMN1; SMN2HPGDTSHRESR2 | |
| SCHEMBL25958553 | 0.82 | VNN1 (0.43) | VNN1SMN1; SMN2HPGDTSHRESR2 | |
| SCHEMBL25958758 | 0.81 | ALOX5AP (0.38) | ALOX5APFEN1 | |
| SCHEMBL25959288 | 0.81 | VNN1 (0.41) | VNN1SMN1; SMN2HPGDTSHRESR2 | |
| SCHEMBL25958820 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDTSHRESR2GRM5 | |
| SCHEMBL25958835 | 0.77 | SCN9A (0.38) | DPP4ALOX5APFEN1 | |
| SCHEMBL25958653 | 0.77 | ALDH1A1 (0.42) | HPGDTSHRNPC1RAB9ADPP4 | |
| SCHEMBL25958773 | 0.72 | SCN9A (0.36) | VNN1HPGDKMT2A | |
| SCHEMBL24058957 | 0.72 | ROCK2 (0.46) | VNN1SMN1; SMN2HPGDTSHRESR2 | |
| SCHEMBL24058963 | 0.72 | VNN1 (0.41) | VNN1SMN1; SMN2HPGDTSHRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870582-B1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2023-07-19 | — | — | EP | disclosed |