Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16591602 | 0.85 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL20939157 | 0.84 | PTGES (0.41) | HSD17B10SMN1; SMN2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL22332274 | 0.82 | HSD17B10 (0.61) | HSD17B10SMN1; SMN2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL25959855 | 0.82 | HSD17B10 (0.40) | HSD17B10SMN1; SMN2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL25962302 | 0.72 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL15337884 | 0.70 | HSD17B10 (0.50) | HSD17B10ALDH1A1YAP1TEAD4CYP2C19 | |
| SCHEMBL16591610 | 0.70 | CYP2D6 (0.45) | HSD17B10SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL22332307 | 0.69 | ALDH1A1 (0.41) | HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL20381510 | 0.68 | ALDH1A1 (0.41) | HSD17B10SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL16591617 | 0.68 | ITGB3 (0.49) | HSD17B10SMN1; SMN2ALDH1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718630-B2 | Compositions and methods for treating cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-08 | — | — | US | disclosed |
| US-20230135350-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135350-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | KRAS, HRAS, NRAS | HSD17B10 3787/4885SMN1; SMN2 3432/4885ALDH1A1 2792/4885 |
| US-11718630-B2 | Compositions and methods for treating cancer | KRAS, HRAS, NRAS | HSD17B10 3787/4885SMN1; SMN2 3432/4885ALDH1A1 2792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.