Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 15/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25959662 | 0.91 | ALOX15 (0.44) | ALOX15KMT2A | |
| SCHEMBL25958274 | 0.90 | RAB9A (0.45) | ALOX15KMT2ALMNA | |
| SCHEMBL25959674 | 0.83 | TSHR (0.49) | KMT2ALMNA | |
| SCHEMBL22257176 | 0.82 | ALOX15 (0.51) | ALOX15KMT2ALMNAPYGLGRM4 | |
| SCHEMBL25959631 | 0.82 | SMN1; SMN2 (0.49) | ALOX15KMT2ALMNA | |
| SCHEMBL25959661 | 0.82 | ALOX15 (0.47) | ALOX15KMT2ALMNA | |
| SCHEMBL25960133 | 0.81 | ALOX15 (0.47) | ALOX15KMT2ALMNAGRM4 | |
| SCHEMBL25959637 | 0.81 | ALOX15 (0.53) | ALOX15KMT2ALMNA | |
| SCHEMBL25959682 | 0.81 | ALOX15 (0.53) | ALOX15KMT2ALMNA | |
| SCHEMBL25960118 | 0.79 | ALOX15 (0.47) | ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248752-A1 | PRODRUGS OF ALOX-15 INHIBITORS AND METHODS OF USING THE SAME | EMPIRICO INC. | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248752-A1 | PRODRUGS OF ALOX-15 INHIBITORS AND METHODS OF USING THE SAME | ALOX15, ALOX5, ALOX15B | ALOX15 1/4885KMT2A 2026/4885LMNA 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.