Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25960279 | 0.88 | PAX8 (0.44) | PAX8POLBSMN1; SMN2RXRANR1H2 | |
| SCHEMBL25960317 | 0.88 | POLB (0.39) | POLBSMN1; SMN2HDAC1MEN1RAB9A | |
| SCHEMBL3365028 | 0.86 | L3MBTL1 (0.43) | PAX8POLBSMN1; SMN2HDAC1RXRA | |
| SCHEMBL3367105 | 0.85 | GAA (0.44) | PAX8HDAC1CA12CA1CA2 | |
| SCHEMBL3368971 | 0.85 | GAA (0.44) | PAX8HDAC1CA12CA1CA2 | |
| SCHEMBL25960268 | 0.83 | PAX8 (0.45) | PAX8SMN1; SMN2HDAC1NR1H2NR1H3 | |
| SCHEMBL8018111 | 0.81 | PAX8 (0.55) | PAX8SMN1; SMN2RXRANR1H2NR1H3 | |
| SCHEMBL16681965 | 0.80 | GPR119 (0.46) | PAX8POLBSMN1; SMN2RXRANR1H2 | |
| SCHEMBL16681968 | 0.80 | PAX8 (0.43) | PAX8POLBSMN1; SMN2RXRANR1H2 | |
| SCHEMBL15809946 | 0.80 | LTB4R (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230244149-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-08-03 | — | — | US | disclosed |